Dihydroxybergamottin Effects Explained

Do you want better results from your dietary supplements? Want to find the best testosterone boosting supplements that suits you? If your answers are a big yes, this blog on Dihydroxybergamottin effects explained will surely be of great interest to you.

6′,7′-dihydroxybergamottin (DHB) can be classified as a furanocoumarin that is generally found in grapefruit juice. One of the best things about Dihydroxybergamottin is that inhibits the oxidation of certain drugs and increases their oral bioavailability. In other words, 6′,7′-dihydroxybergamottin (DHB) improves the absorption of certain drugs so they remain longer in the bloodstream. This helps you get better results while making use of dietary supplements.

An “anabolic amplifier”, 6′,7′-dihydroxybergamottin (DHB) is globally renowned for its unique ability to inhibit the activity of the cytochrome P450 CYP3A4 enzyme in the liver and intestine that is responsible to reduce the absorption of small foreign organic molecules. Studies have reported that in vivo and vitro hydroxylation at 6-beta-position catalyzed by CYP3A4 enzyme occurs for progesterone, testosterone, androstenedione, and cortisol along with a wide range of synthetic compounds such as budesonide, dexamethasone, and Methandrostenolone (metandienone [trade names Averbol, Dianabol, Danabol, Dbol]). However, it is important to remember that greater bioavailability can lead to greater toxicity and, therefore, on-cycle support and post-cycle therapy become more important than ever to avoid side effects such as oily skin, acne, bloating, or gynecomastia.

6′,7′-dihydroxybergamottin is also effective to stabilize scare and relieve sickness. It has the unique ability to relieve pain and facilitate smooth circulation of blood in the body. Known for its disintoxicating effects, 6′,7′-dihydroxybergamottin can also hold the digestion bowel movements. It is also known to restore the natural color of hair and is often used as a remedy for dandruff.

This naturally-occurring inhibitor of cytochrome P450 3A4 is gaining popularity as a potent ingredient in sports nutrition and bodybuilding supplements, primarily because of the pharmacokinetic-boosting effects of grapefruit juice. Today, Dihydroxybergamottin is commonly added to dietary supplements to intensify levels of testosterone. It is also added to fat burners, nitrogen boosters, and pre-workout creatine stacks.

Dihydroxybergamottin is primarily used to inhibit the oxidation of certain drugs to increase the oral bioavailability of many CYP3A4 substrates cyclosporine (INN, ciclosporin). It can also inhibit the activation of carcinogens. It is worthwhile to note here that grapefruit (specifically furanocoumarin) can inhibit the special enzymes in the walls of the small intestine that is responsible for the destruction of many medications and prevent their proper absorption in the body. When grapefruit juice inhibits the action mechanism of the enzyme, the drugs are allowed to freely enter the body and this improves the rate of absorption.

Let us have a close look at some steroid cycles involving DHB.

6′,7′-dihydroxybergamottin (DHB) is best stacked with Halovar and Epistane. The best thing about 6′,7′-dihydroxybergamottin (DHB) is that it improves the efficacy of a large majority of oral supplements. Therefore, it can be stacked with almost all oral supplements during a cutting, bulking or recomposition cycle. Ideally, 6′,7′-dihydroxybergamottin (DHB) should be used in conjunction with your on-cycle support and post-cycle therapy regimen when using prohormones. DHB is usually combined with 3,4-divanillyltetrahydrofuran (nettle root extract).

Under no circumstances should 6′,7′-dihydroxybergamottin (DHB) be abused or overdosed, as it may lead to 6′,7′-dihydroxybergamottin (DHB) side effects such as increased heart rate, palpitations or increased sweating. 6′,7′-dihydroxybergamottin (DHB) is not recommended for children. It is also not recommended for pregnant, breastfeeding or nursing women. 6′,7′-dihydroxybergamotine (DHB) should not be taken by people taking cholesterol medicines, urinary tract medicines, HIV medicines, anticoagulants, calcium antagonists (blood sugar medicines), intestinal medicines, medicines for impotence and psychiatric and psychotic medicines.